Hua
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Nga kupu taurite:4(1H)-Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4 -dihydropyrimidin-4-one;2,6-Diamino-4(1H)-pyrimidinone;2,6-Diamino-4(3H)-pyrimidinone;2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4 -pyrimidinol;2,6-Diaminopyrimidin-4-one;2,6-Diaminopyrimidine-4(3H)-one;6-Aminoisocytosine;6-Hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Taonga matū o 2,4-Diamino-6-hydroxypyrimidine
● Te ahua/Tae: ma te totoka
● Te Kohu Kohu:0.00232mmHg i te 25°C
● Ira Whakarewa:285-286 °C (dec.)(marama)
● Taupū Refactive:1.7990 (whakatau)
● Ira Kohua:288.5 °C i te 760 mmHg
● PKA:10.61±0.50(I Matapaetia)
● Ira Kohiko:128.3 °C
● PSA：98.05000
● Kiato:1.84 g/cm3
● RangitakiP:0.50900
● Rokiroki Temp.:Desiccate ki +4°C
● Tairongo.:Maama Maama
● Wairewa.:DMSO (Paku), Methanol (Paku)
Pure/Kounga
99% *nga raraunga mai i nga kaiwhakarato mata
2,4-Diamino-6-hydroxypyrimidine * raraunga mai i nga kaiwhakarato reagent
Nga korero haumaru
● Pikito/ngā:
Xi
● Waehere morearea:Xi
● Nga korero:36/37/38
● Tauākī Haumaru:22-24/25-36-26
Whai hua
● Whakaahuatanga: Ko te 2,4-Diamino-6-hydroxypyrimidine (DAHP) he mea whiriwhiri, he aukati motuhake o te GTP cyclohydrolase I, ko te taahiraa whakaheke tere mo te de novo pterin synthesis.I roto i nga pūtau HUVEC, ko te IC50 mo te aukati i te BH4 biosynthesis he 0.3 mM.Ka taea te whakamahi i te DAHP ki te aukati tika i te hanga KORE i roto i nga momo pūtau maha.
● Nga Whakamahinga: Ko te 2,4-Diamino-6-hydroxypyrimidine (DAHP) he mea whiriwhiri, he aukati motuhake o te GTP cyclohydrolase I, ko te taahiraa whakaiti reiti mo te whakahiato o te pterin de novo.I roto i nga pūtau HUVEC, ko te IC50 mo te aukati i te BH4 biosynthesis he 0.3 mM.Ka taea te whakamahi i te DAHP ki te aukati i te hanga KORE i roto i nga momo pūtau maha. Ko te 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) he pūhui whai hua ki te whakahiato waro.
Ko te 2,4-Diamino-6-hydroxypyrimidine he pūhui matū me te tātai rāpoi C4H6N4O.Kei te whakamahia hei takawaenga i roto i te whakahiato o nga momo puhui, tae atu ki nga rongoa rongoa me nga waikano.He hanganga mowhiti pyrimidine te puhui kei roto e rua nga roopu amino (NH2) me tetahi roopu hydroxyl (OH) e piri ana ki nga ngota waro rereke.Ko tenei hanganga ka waiho hei poraka hanga maha mo te whakahiatotanga o nga ngota ngota uaua ake.2,4-Diamino-6-hydroxypyrimidine ka taea e nga momo tikanga waihanga, tae atu ki te tauhohenga o te cyanamide me te Urea.He maha nga tono i roto i te umanga rongoa, ina koa ki te whakahiato o nga raau taero anticancer me nga paturopi.
