Hua
Dicyclohexylcarbodiimiedimiloside; cas Nama: 538-75-0
Hangai: Dccd; dicyclohexylcarbodimiside
Rawa matū o te dicyclohexylcarbodimide
● Te ahua / Tae: totoka kore
● Te pehanga o te Vapor: 1.044-1.15PA i te 20-25 ℃
● Melting Point: 34-35 ° C (lit.)
● Whakakorehia te Index: N20 / D 1.48
● kohua te wāhi: 277 ° C i te 760 mmhg
● Flash Point: 113.1 ° C
● PSA:24.72000
● Te Whakataetae: 1.06 G / CM3
● LOGP: 3.82570
● Te rokiroki o te Techth.:Store i te RT.
● tairongo.
● Kohukohu.:methylene Chloride: 0.1 G / ML, maamaa, kore
● te whakamahinga wai .: utu
● Xlogp3: 4.7
● Ko te nama takoha hardrogen: 0
● Te Whakawhiwhinga Bondrogen Bondor: 2
● Ko te tatauranga here hurihuri: 2
● Massiply tuturu: 206.17829710
● Te tatau ngota taumaha: 15
● matatini: 201
● Transport Dot Label: Poison
Nga korero mo te Haumaru
● Whakaahua:
T,
Whakaahua xna
● Nga Waehere Whakatau: T, XN, T +
● Tauākī: 23/1 24/24-40-43-46 / 38-21-24-22-62-37 / 38-10-61-26-38-26-38-20 / 22
● Nga korero mo te Haumaru: 26-36 / 39 / 39-45-41-24-37 / 39-24 / 25-36-16-53-28
Whaipainga
Akomanga matū:Te hauota hauota -> etahi atu pūhui hauota
Ataata cantical:C1ccc (cc1) n = c = nc2cccc2
Whakaahuatanga:Ka whakamahia te carbodimilomika dicydoxyl i roto i te peptide matū hei tohutoro. He mea pouri noa, he tangata mohio, a ka pa atu ki a Dermatitis i nga kaitakaro me nga kaimahu.
Whakamahia:I roto i te whakahiato o te peptaides. Ko te hua nei e whakamahia ana i Amikacin, Glutatione Dehydrants, tae atu ki te whakahiato o te waikawa waikawa, alehyde, ketonenate; I te wa e whakamahia ana hei kaiwhakatakoto i roto i te riihi, ka tau ki te dicyclohexyluda na roto i te tauhohenga poto i raro i te pāmahana noa. Ka taea hoki te whakamahi i tenei hua ki te whakahiato o te peptide me te waikawa waikawa. He mea ngawari ki te whakamahi i tenei hua ki te urupare ki te whakahiato o te Carboxy koreutu me te amino-a-iwi ki te peptade. E whakamahia whānuitia ana tenei hua ki te rongoa hauora, hauora, hanga-taputapu me nga hua koiora, me etahi atu mara hangai. N, N'-dicyclohexylcarbodimimorimillbodimimorimode Ko te carbodimide i whakamahia ki te tokorua i te waikawa amino i te wa o te whakahiato peptide. N, e whakamahia ana a N'-dicyclohexylcarimillbodiide hei kaihoko dehydrating mo te whakarite i nga amiside, nga ketone, nga taangata tae atu ki te waipuke me te whakapae mo te waipiro tuarua. Ka whakamahia te dicyclohexylcarbodiside hei kaihoko dehydrating i te pāmahana rūma i muri i te waa tauhohenga poto, i muri i te hua o te tauhohenga he dicyclohexylrea. Ko te hua he tino ngoikore i roto i te whakarewa raupaparorohiko, na reira ko te wehe ngawari o te hua tauhohenga.
Whakataki taipitopito
Dicyclohexylcarbodiimimode (DCC) he reagent e whakamahia ana i roto i te whakahiato rauropi. He maaka ma te puhoi i roto i te wai me te rewa i roto i nga whakarewa o te tipu penei i te ethyl acetate me te dichloomethane.
I whakamahia tuatahi te DCC hei kaihoko honohono i roto i te kohinga peptis me etahi atu tauhohenga e pa ana ki te waihanga o nga here here. Ka whakatairanga i te kohinga o te waikawa carboxyic me te amine, te arahi ki te hanganga o nga amisideni. Ka tutuki i tenei ma te whakahohe i te roopu waikawa carboxy e whakahaere ana i te whakaekenga o te apine i runga i te waro honi kua whakahohehia.
I tua atu i te kohinga peptide, ka whakamahia ano hoki a DCC i etahi atu tauhohenga o te rauropi, penei i te mahi whakakoiraa me te tauhohenga. Ka taea te mahi ki te hanga i nga kaimoana mai i te waikawa carboxy, a ki te huri i nga kohinga waikawa hakihaki (penei i nga kowhatu carloboxy, me te waikawa hakinakina, me te whakahohe esters) ki waenga.
E mohiotia ana a DCC mo tona kaha kaha ki te whakatairanga i te hanganga here a te ahotea me te whakariterite me te whānuitanga o nga roopu mahi. Heoi, e kiia ana he makuku-makuku-te whai kiko, ka taea te whakakore i te wai ki te wai, ki te tino pai ranei. Na reira, ka whakahaerehia te tikanga me te penapena i raro i nga tikanga ahuru.
He mea nui kia tupato ki nga mahi e mahi ana me te DCC, na te mea ka taea te riri ki te kiri, te kanohi, me te punaha manawa. Me whakamahi te waikoretanga tika me nga taputapu whakamarumaru whaiaro i tona ringa.
Puka tono
Ka kitea e te dicyclohexylcarbodiimire (DCC) nga momo tono i roto i te whakahiato rauropi, ina koa i te mara o te matū peptally. Anei etahi tono rongonui o te DCC:
Kohatu Peptide:E whakamahia ana a DCC i te mea he kaihoko honohono i te kohinga peptis hei whakauru atu ki te waikawa amino me te hanga here. E whakatairanga ana i te tauhohenga whakaurunga i waenga i te roopu whakairo o tetahi Amino Anino me te roopu a Amino tetahi atu, e arahi ana ki te hanganga o nga here peptide.
Te uruparenga o te Etirication:Ka taea te whakamahi i te DCC ki te huri i te waikawa carboxy ki roto i nga kaihoroi ma te whakaohooho i a raatau ki te waipiro. I te aroaro o te DCC, ka whakahohehia te waikawa Carboxylic, ka taea te whakaeke i te waikawa na te waipiro hei hanga i te ester. He pai tenei tauhohenga ki te whakahiato o nga mahi mo nga momo tono.
Te tauhohenga Amuidation:Ka taea e te DCC te whakahaere i te waikawa o te waikawa carboxylic, te waikawa waikawa, te waikawa anhydrides, me te whakahohe i nga emers. Ka taea e te urupare i waenga i te huringa waikawa carboxy me te apine hei hanga i tetahi here amide. Ka kitea e tenei tono te whaipainga i roto i te whakahiato o nga amihana, he mea nui ki nga momo rauropi me nga matū.
Te tauhohenga UGI:Ka taea te whakamahi a DCC i te tauhohenga UGI, he urupare maha e pa ana ki te tuku o te apine, he isocyanide, he pūhui waro, me te waikawa. Ka awhina a DCC ki te whakahohe i te roopu Carboxyl o te waikawa, ka taea e koe te urupare me te apine ka hangaia he here amine.
Huarahi tarukino:I te nuinga o te wa e mahi ana te DCC i roto i te umanga rongoā mo te whakahiatotanga o nga kaitono tarukino me nga taonga rongoā kaha (APIS). Ko tana whakamahinga i roto i te kohinga peptide, nga mahi whakaari, me etahi atu rereke rereke ka waiho hei rongoa mo te mate tarukino me nga tukanga whanaketanga.
He mea tika ki te tohu he maha atu o nga tono a DCC i roto i te whakahiato o te tipu, tae atu ki te hanganga o Ureas, carbamates, me nga hydrazides. Ko tana pukenga me te hototahi me nga momo roopu mahi he taputapu nui i roto i te pouaka taputapu o nga kaiwhakamahara miihini.
