L-Malic acid

Whakaahuatanga Poto:

Ingoa Hua:L-Malic acid

kupu taurite:L-(-)-Wakawa Malic, CP;Wakawa Butanedioic, 2-hydroxy-, (2S)-;pinguosuan;Butanedioicacid,hydroxy-,(S)-;waiwai-,(S)-Butanedioicacid;l-(ii) -malicacid;L-Gydroxybutanedioicacid;L-Mailcacid

CAS:97-67-6

MF:C4H6O5

MW:134.09

EINECS:202-601-5

Ngā Kāwai Hua:Nga tangohanga tipu;Aliphatics;MalicAcidSeries;Carboxylic Acids (Chiral);Chiral chemicals;Chiral Reagents;Kai me te Whangai ADDITIVES;Chiral Building Blocks;mo te Whakataunga o nga Turanga;Optical Resolution;Syntetic Organic Chemistry;Kai tāpiritanga me te waikawa acidic;Hemidterazole. bc0001

Kōnae Mol:97-67-6.mol

Tukuna he imeera ki a matou

Taipitopito Hua

Tohu Hua

Malic acid Huahanga matū

Te rewa	101-103 °C (marama)
alpha	-2º (c=8.5, H2O)
Kohuatanga	167.16°C (whakatau tata)
kiato	1.60
pehanga kohu	0Pa i te 25 ℃
taupū huritao	-6.5 ° (C=10, Acetone)
FEMA	2655 \|L-MALIKA KAUPAPA
Fp	220 °C
pāmahana rokiroki.	Whakaorangia ki raro +30°C.
whakarewatanga	H₂O: 0.5 M i te 20 °C, maamaa, kore tae
puka	Paura
tae	Mā
Te Kaha Tauwhāiti	1.595 (20/4 ℃)
PH	2.2 (10g/l, H2O, 20 ℃)
pka	(1) 3.46, (2) 5.10(i te 25 ℃)
mahi whatu	[α]20/D 30±2°, c = 5.5% i roto i te pyridine
Wairewa wai	wairewa
Merck	14,5707
Nama JECFA	619
BRN	1723541
InChIKey	BJEPYKJPYRNKOW-REOHCLBHSA-N
RangitakiP	-1.68
CAS Raraunga Raraunga Tohutoro	97-67-6(Tuhinga Raraunga CAS)
Tohutoro Matū NIST	Te waikawa Butanedioic, hydroxy-, (s)-(97-67-6)
Pūnaha Rehita Matū EPA	Te waikawa Butanedioic, 2-hydroxy-, (2S)- (97-67-6)

Nga korero haumaru

Waehere morearea	Xi
Tauākī mōrearea	36/37/38
Tauākī Haumaru	26-36-37/39
WGK Tiamana	3
RTECS	ON7175000
TSCA	Ae
Waehere HS	29181980

Te Malic acid Te Whakamahinga me te Synthesis

Whakaahuatanga	Ko te waikawa L-Malic e tata kore hongi (i etahi wa he haungi, he kakara kino) me te reka, te reka waikawa.Kare he pupuhi.Ka taea te whakarite ma te whakamakuku i te waikawa maleic;ma te fermentation mai i te huka.
Ngā Āhuatanga matū	Ko te waikawa L-Malic he haunga kore noa (i etahi wa he haungi, he kakara kino).He kawa, kawakawa, karekau te reka o tenei puhui.
Ngā Āhuatanga matū	he otinga kore tae
Putanga	Ka puta i roto i te wai maple, te aporo, te merengi, te papaya, te pia, te waina karepe, te koko, te sake, te kiwifruit me te pakiaka chicory.
Whakamahinga	Ko te waikawa L-Malic e whakamahia ana hei taapiri kai, Tiwhikete α-amino tauhohenga tiaki mo nga waikawa amino.Ko te synthon maha mo te whakarite i nga puhui chiral tae atu ki nga agonists kaiawhina κ-opioid, 1α,25-dihydroxyvitamin D3 analogue, me te phoslactomycin B.
Whakamahinga	Ko te ahua o te ahua L i kitea i roto i nga aporo me etahi atu hua me nga tipu.Ko te reagent tiaki α-amino whiriwhiri mo nga pärönaki waikawa amino.Synthon maha mo te whakarite i nga puhui chiral tae atu ki te κ-opioid rece
Whakamahinga	Takawaenga i roto i te whakahiato matū.Ko te Chelating me te Kaipupuri.Te kai whakakareka, te whakakaha reka me te waikawa i roto i nga kai.
Whakamaramatanga	ChEBI: He ahua kaha o te waikawa malic he (S)-whirihoranga.
Whakaritenga	Ka taea te whakarite i te waikawa L-Malic na roto i te hydration o te waikawa maleic;ma te fermentation mai i te huka.
Whakaahuatanga Whanui	Ko te waikawa L-Malic he waikawa waro e kitea ana i roto i te waina.Ka whai wāhi nui ki te noho pūmautanga microbiological waina.
Nga Mahi Biochem/physiol	Ko te waikawa L-Malic he wahanga o te kaiaka pūkoro.Ko tana tono ka mohiotia i roto i nga rongoa.He pai ki te maimoatanga o te hepatic hepatic, whai hua ki te hyper-ammonemia.Ka whakamahia hei waahanga o te whaowhia waikawa amino.Ko te waikawa L-Malic ano he nanomedicine i roto i te maimoatanga o nga mate neurological roro.He TCA (huringa Krebs) takawaenga me te hoa i roto i te waka waka aspartate waikawa malic.
Nga Tikanga Pure	Whakatioatitia te waikawa S-malic (wao) mai i te ethyl acetate/pet ether (b 55-56o), kia noho te pāmahana ki raro i te 65o.Ka memeha ranei ma te whakakoi ki roto i nga wahanga tekau ma rima o te diethyl ether anhydrous, decant, whakakorikori ki te hautoru o te rōrahi, ka whakatioataatatia ki te 0o, toia ki te rewa tonu.[Beilstein 3 IV 1123.]